Bioactive Small Molecules
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Filtered Search Results
STEMCELL Technologies Thiazovivin, Size: 5 mg
Thiazovivin is a selective inhibitor of Rho-associated coiled-coil containing protein kinase (ROCK), a serine/threonine kinase that plays a role in cell polarity, contraction, and actin cytoskeleton reorganization (Xu et al.). Thiazovivin is effective at 5-fold-lower concentrations than another common ROCK inhibitor Y-27632 (Catalog #72302; Xu et al.).MAINTENANCE AND SELF-RENEWAL· Promotes survival of human embryonic stem (ES) cells during dissociation by stabilizing E-cadherin and improves cell attachment (Xu et al.).· Promotes survival of single human induced pluripotent stem (iPS) cells during transfection for TALEN-mediated genome editing (Sun and Zhao).REPROGRAMMING· Increases the efficiency of reprogramming human somatic cells to iPS cells, in combination with PD0325091 and SB431542 (Lin et al.).· Increases the efficiency of reprogramming human cord blood mononuclear cells to iPS cells (Hu et al.).
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Medchemexpress LLC Retatrutide, 99.96%, 10mg
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Retatrutide (LY3437943) is a triple agonist peptide of the glucagon receptor (GCGR), glucosedependent insulinotropic polypeptide receptor (GIPR), and glucagon-like peptide-1 receptor (GLP-1R). Retatrutide binds human GCGR, GIPR, and GLP-1R with EC50 values of 5.79, 0.0643 and 0.775 nM, respectively. Retatrutide can be used for the research of obesity.
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STEMCELL Technologies Valproic Acid (Sodium Salt), Size: 500 mg
Inhibit Histone Deacetylases (HDACs) with Valproic Acid (VPA). This epigenetic modifier modulates osteogenic differentiation of human mesenchymal stem cells (Cho et al. J Cell Biochem, 2005), and together with other factors, it allows for the direct lineage reprogramming of fibroblasts to mature neurons (Hu et al. Cell Stem Cell, 2015) and the reprogramming of human fibroblasts to iPS cells (Huangfu et al. Nat Biotechnol, 2008). VPA is used to promote the proliferation and self-renewal of human and mouse hematopoietic progenitor cells (Bug et al. Cancer Res, 2005, De Felice et al. Cancer Res, 2005) and suppress differentiation of astrocytes and oligodendrocytes from rat neural progenitor cells (Hsieh et al. Natl Acad Sci USA, 2004, Jung et al. BMC Cell Biol, 2008). Valproic Acid is supplied as a sodium salt of the molecule with ≥ 95% purity; Molecular weight 166.2 g/mol; CAS number 1069-66-5. Visit STEMCELL.com for more information and related products.
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Invivogen H-151 STING INHIBITOR 10MG
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Synthetic Indole Derivative - STING Inhibitor - InvitroFit
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ADIPOGEN CORPORATION RETATRUTIDE SODIUM SALT 1MG
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NC2584002 RETATRUTIDE SODIUM SALT 1MG
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APEXBIO TECHNOLOGY LLC N3-KETHOXAL 5MG
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NC2048518 N3-KETHOXAL 5MG
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Active Motif Trichostatin A
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Active Motif's Trichostatin A is a potent and selective histone deacetylase (HDAC) inhibitor (Ki = 3.4 nM). It induces reversion of ras-transformed cells to normal morphology and induces dedifferentiation of primordial germ cells into embryonic germ cells. It is cell permeable, and is active in vivo.
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Medchemexpress LLC Nemolizumab 5Mg | HY-P99162-5MG
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Nemolizumab 5Mg
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Medchemexpress LLC Fitc-Dextran Mw 4000 50Mg | HY-128868A-50MG
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Fitc-Dextran Mw 4000 50Mg
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Medchemexpress LLC Polyinosinic-Polycytidylic 5Mg | HY-107202-5MG
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Polyinosinic-Polycytidylic 5Mg
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Medchemexpress LLC A 83-01 5Mg | HY-10432-5MG
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A 83-01 5Mg
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Medchemexpress LLC Lysostaphine 5Mg | HY-P2329-5MG
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Lysostaphine 5Mg
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Selleck Chemical LLC Trametinib (GSK1120212) 10mg 871700-17-3 JTP-74057, Mekinist
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Trametinib (GSK1120212, JTP-74057, Mekinist) is a highly specific and potent MEK1/2 inhibitor with IC50 of 0.92 nM/1.8 nM in cell-free assays, no inhibition of the kinase activities of c-Raf, B-Raf, ERK1/2. Trametinib activates autophagy and induces apoptosis. *For Research & Development use only. Product is not intended for drug, household, or human consumption.
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Selleck Chemical LLC Dibutyryl-cAMP sodium salt, 2 g, powder, 99.96% purity, off-white
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Dibutyryl-cAMP sodium salt, 2 g, powder, 99.96% purity, off-white
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Medchemexpress LLC Methotrexate 10Mm 1Ml In Dmso | HY-14519-10MM-DMSO
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Methotrexate 10Mm 1Ml In Dmso
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